Probing Substrate Sequestration in Carrier Proteins using Vibrational Spectroscopy Labels and Molecular Dynamic Simulations
نویسندگان
چکیده
منابع مشابه
Probing the Phosphopantetheine Arm Conformations of Acyl Carrier Proteins Using Vibrational Spectroscopy
Acyl carrier proteins (ACPs) are universal and highly conserved domains central to both fatty acid and polyketide biosynthesis. These proteins tether reactive acyl intermediates with a swinging 4'-phosphopantetheine (Ppant) arm and interact with a suite of catalytic partners during chain transport and elongation while stabilizing the growing chain throughout the biosynthetic pathway. The flexib...
متن کاملCorrection to “Probing the Phosphopantetheine Arm Conformations of Acyl Carrier Proteins Using Vibrational Spectroscopy”
■ REFERENCES (1) Corrected ref 2: Nguyen, C.; Haushalter, R. W.; Lee, D. J.; Markwick, P. R. L.; Bruegger, J.; Caldara-Festin, G.; Finzel, K.; Jackson, D. R.; Ishikawa, F.; O’Dowd, B.; McCammon, J. A.; Opella, S. J.; Tsai, S.-C.; Burkart, M. D. Nature 2014, 505, 427. (2) Corrected ref 3: Masoudi, A.; Raetz, C. R. H.; Zhou, P.; Pemble, C. W., IV. Nature 2014, 505, 422. (3) Corrected ref 4: Dutta...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2018
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2017.11.423